Most dictionaries list irregardless as non-standard English and advise against its use in speech and writing. It is an illogical formation, since it contains a double negative: the negative prefix ir- (meaning “not”), combined with the negative suffix -less.
The correct word is regardless. The word irrespective is also correct and may replace regardless in the expression regardless of.
Use regardless as an adverb meaning “anyway” or “nonetheless”:
- The deadline seems unrealistic, but we’ll get the job done regardless (anyway).
Use regardless of or irrespective of as a preposition meaning “in spite of” or “without regard to”:
- Joe continued to sing regardless of (in spite of) the jeers and shouts from the audience.
- Candidates will be selected on merit, irrespective of (without regard to) their age or gender.
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