The prefix de- has several meanings.
Meaning 1: reverse (an action)
- The company decentralized its manufacturing and built factories across the country.
Meaning 2: remove
- The aircraft was de-iced.
Meaning 3: decrease
- With voltage derating, electrical devices last longer.
Meaning 4: get off of
- The passengers deplaned and then went through customs.
Meaning 5: down, away
- She descended the stairs.
Meaning 6: completely
- The trees were denuded of their leaves.
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